Comparative Study of Over-the-Counter Whitening Agents

The demand for effective and safe over-the-counter (OTC) whitening products has led to the development of various formulations, including those based on PAP.

  • Study Overview: This research investigated the whitening effect, cytotoxicity, and enamel surface alterations induced by different OTC bleaching agents, including PAP, in comparison to hydrogen peroxide.

  • Key Findings:

    • Whitening Efficacy: All tested agents resulted in a greater color difference compared to the negative control, with hydrogen peroxide showing the greatest change.

    • Enamel Safety: PAP treatment showed no enamel surface changes, in contrast to hydrogen peroxide, which caused mild interprismatic dissolution.

    • Cytotoxicity: PAP was among the agents that did not exhibit cytotoxic effects.

  • Conclusion: PAP-based whitening agents are effective in stain removal and present a safer profile concerning enamel integrity and cytotoxicity compared to traditional peroxide-based products.

Reference: Torres, C. R. G., et al. (2021). Effectiveness and Safety of Over-the-Counter Tooth-Whitening Bleaching Agents. International Journal of Environmental Research and Public Health, 18(24), 13023. Link

 

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